A camlock closure lockout device restricts access to a bulk pot camlock closure when the blast pot is pressurized. The Allredi Camlock Closure Lockout Device can be installed over the 10” camlock closure of most manufacturers bulk pots. When the blast pot pot is pressurized, a pneumatic signal activates a pneumatically actuated piston, securing the camlock closure lockout device and prohibiting access to the camlock closure. When the blast pot is depressurized, the pneumatic signal is removed, unlocking the camlock closure lockout device and allowing access to the camlock closure on the blast pot.